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HRT8 min read

Types of HRT Available in the UK: Patient Information Guide (2026)

Patient information on UK HRT delivery formats — transdermal gels and patches, oral tablets, sprays, vaginal products and testosterone for women. UK regulations restrict advertising prescription medicines, so this page does not display medicine-brand prices.

TreatCompare Editorial Team · Healthcare Price Research

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Reporting period
2026-05-13
Last updated
2026-05-13
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Important information for UK consumers. HRT products are prescription-only medicines (POMs) in the UK. UK Human Medicines Regulations 2012 restrict the advertising of prescription medicines to the public, so this article is general patient information about HRT delivery formats — it is not an advertisement, not an offer of sale, and not medical advice. Which HRT type and licensed product is clinically appropriate for you is a decision for a UK-registered prescriber following an assessment. Medicine prices are set by the dispensing pharmacy at the point of dispensing and are not displayed on consumer comparison pages.

What types of HRT are available in the UK? This guide explains the delivery formats (gel, patch, tablet, spray, vaginal) and pharmacological categories (oestrogen-only, combined, progesterone-only, testosterone) used in UK private HRT, with the questions to ask before deciding with a prescriber.

Oestrogen — the core of HRT

Oestrogen replaces the hormone that declines during menopause. It is available in several delivery formats:

Transdermal (through the skin) — recommended first choice

Delivery formatHow it's usedWhy it's chosen
Transdermal gelDaily application to the skin (pump or sachet)Steady-state absorption, easy dose titration
Transdermal patchApplied twice weeklyContinuous absorption, no daily application
Transdermal spraySprayed on the forearm dailyDries quickly, alternative for patch sensitivity

NICE guidelines recommend transdermal oestrogen (gel, patch or spray) as the first choice for most women. Transdermal oestrogen does not increase the risk of blood clots, unlike oral oestrogen tablets.

Oral (tablets)

Oral oestrogen tablets are taken daily. Several licensed products are available in the UK. They are effective but carry a slightly higher risk of venous thromboembolism (blood clots) compared to transdermal options. They may not be suitable if you have a history of DVT, migraines with aura, or BMI over 30. The specific licensed product is a clinical decision for the prescriber.

Progesterone — essential for women with a uterus

If you have a uterus, you must take progesterone alongside oestrogen to protect the womb lining. The main UK options by pharmacological category:

Delivery formatWhat it isPattern
Body-identical micronised progesteroneDaily oral or vaginal capsuleSame molecular structure as natural progesterone; preferred current UK practice
Combined patch (continuous)One patch delivers oestrogen and progestogen continuouslySingle patch for postmenopausal women
Combined patch (sequential)Oestrogen-only patches then combined patches in a cycleSuitable for perimenopausal women who still cycle
Combined tablet (continuous or sequential)Oral tablet delivering both hormonesCycle pattern depends on menopausal stage
Intrauterine progesterone systemInserted device, lasts several yearsHigher one-off fitting cost, lower ongoing

Body-identical micronised progesterone is the preferred option in current UK practice. It has the same molecular structure as the progesterone your body naturally produces.

Testosterone (off-label for women)

Testosterone is increasingly recognised as important for women during menopause, particularly for:

  • Low libido
  • Fatigue and low energy
  • Brain fog and poor concentration

There is currently no testosterone preparation licensed in the UK for women. Specialists prescribe off-label products in line with British Menopause Society guidance, with blood-test monitoring of levels. The specific product and dose are clinical decisions for the prescriber.

Vaginal oestrogen

For vaginal dryness, discomfort, and urinary symptoms. Can be used alongside systemic HRT or on its own:

Delivery formatHow it's usedPattern
Vaginal pessary (tablet-shaped)Inserted with applicatorLow-dose, local effect, minimal systemic absorption
Vaginal creamApplied with applicatorLocal urogenital relief
Vaginal ringWorn for 3 months at a timeContinuous low-dose delivery

A vaginal oestrogen product is now available over the counter in the UK for women aged 50+ with vaginal dryness symptoms — no prescription required.

Body-identical vs bioidentical

  • Body-identical HRT: Has the same molecular structure as human hormones. MHRA-regulated. Available on the NHS and privately.
  • Bioidentical HRT (compounded): Custom-compounded in specialist pharmacies. Not regulated by the MHRA. More expensive. Used by some private clinics but not recommended by NICE or the British Menopause Society.

For most women, regulated body-identical HRT is the recommended choice.

Typical first-year service-level cost

ComponentService cost range
Initial consultation£49–£395
Follow-up consultations (2–3)£100–£600
Blood tests (2–3)£100–£300
Service-level subtotal£249–£1,295
Medicine cost (dispensed by GPhC-registered pharmacy)Priced separately by the dispensing pharmacy at the point of dispensing — not displayed on consumer pages under UK regulations

The medicine itself is set by the dispensing pharmacy and varies by licensed product, dose and supply length. Ask the pharmacy for an itemised dispensing receipt.

Patient information and verified UK menopause specialist directory.

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Frequently asked questions

What delivery formats of oestrogen HRT are available in the UK?

Transdermal options are the NICE first choice: oestrogen gels (applied daily), oestrogen patches (applied twice weekly) and oestrogen spray (applied to the forearm daily). Oral oestrogen tablets are also available but carry slightly higher venous thromboembolism risk. The specific licensed product within each format is a clinical decision for the prescriber. UK Human Medicines Regulations 2012 restrict the advertising of prescription medicines to the public, so this page does not display medicine-brand prices.

Which progesterone is recommended in UK HRT?

Body-identical micronised progesterone is preferred in current UK practice because it has the same molecular structure as the progesterone your body naturally produces. Synthetic progestogens are also used, often in combined patches or tablets that deliver oestrogen and progestogen together. Women with a uterus must take progesterone alongside oestrogen to protect the womb lining. The specific licensed product is a clinical decision for the prescriber.

What is body-identical HRT vs bioidentical HRT?

Body-identical HRT has the same molecular structure as human hormones (oestradiol, micronised progesterone). It is MHRA-regulated and available on the NHS and privately. Bioidentical (compounded) HRT is custom-mixed in specialist pharmacies, is not MHRA-regulated, costs more, and is not recommended by NICE or the British Menopause Society (BMS). For most women, regulated body-identical HRT is the recommended choice.

Is testosterone licensed for women in the UK?

No — there is currently no testosterone preparation licensed in the UK for women. It is prescribed off-label by menopause specialists in line with BMS guidance, particularly for low libido, fatigue, and brain fog when systemic HRT alone has not relieved these symptoms. Prescribers monitor levels with blood tests. The specific product is a clinical decision for the prescriber.

Can I get HRT over the counter in the UK?

Yes — there is now a vaginal oestrogen product available over the counter in the UK for women aged 50+ with vaginal dryness symptoms. No prescription is required. All other HRT (systemic oestrogen, progesterone, testosterone) requires a prescription from a UK-registered prescriber following a clinical assessment.

How much does the first year of private HRT cost?

Service-level costs total approximately £600–£2,000+ for the first year, broken down roughly as: initial consultation £49–£395, follow-up consultations £100–£600, blood tests £100–£300, plus the cost of the medicine itself (priced by the dispensing pharmacy, not displayed on consumer pages under UK regulations). Compare consultation and follow-up prices across UK menopause specialists.

What HRT delivery formats treat vaginal dryness?

Local vaginal oestrogen is the standard treatment for vaginal dryness and other urogenital symptoms of menopause. Available delivery formats include vaginal pessaries (tablet-shaped, inserted with an applicator), vaginal creams, and a vaginal ring. Local vaginal oestrogen has minimal systemic absorption and can be used alongside systemic HRT or on its own.

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