GLP-1 Weight-Management Medicines in the UK: Patient Information (2026)
Patient information about the GLP-1 receptor agonists used for weight management or type 2 diabetes in the UK — Mounjaro, Wegovy, Ozempic, Rybelsus, Nevolat. No prescription-medicine prices.
Important context
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- Source type
- TreatCompare compiled research
- Primary source
- Provider-published information and TreatCompare research
- Reporting period
- 2026-05-12
- Last updated
- 2026-05-12
- Figure type
- Mixed sources
- Use
- Research and comparison only
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Important information for UK consumers. The medicines covered in this article are prescription-only medicines (POMs) in the UK. UK regulations restrict the advertising of prescription medicines to the public, so this article is general patient information — it is not an advertisement, not an offer of sale, and not medical advice. This article does not display UK prices for any of the medicines mentioned.
GLP-1 medicines used in the UK
| Brand (active ingredient) | Manufacturer | UK indication | Administration |
|---|---|---|---|
| Mounjaro (tirzepatide) | Eli Lilly | Weight management; separately licensed for type 2 diabetes | Weekly subcutaneous injection |
| Wegovy (semaglutide 2.4mg) | Novo Nordisk | Weight management | Weekly subcutaneous injection |
| Ozempic (semaglutide) | Novo Nordisk | Type 2 diabetes (off-label use for weight management is a clinical decision) | Weekly subcutaneous injection |
| Rybelsus (oral semaglutide) | Novo Nordisk | Type 2 diabetes | Daily oral tablet |
| Nevolat (liraglutide) | Zentiva | Weight management (the generic equivalent of the discontinued Saxenda) | Daily subcutaneous injection |
Tirzepatide is the only dual GIP/GLP-1 receptor agonist in this group. The others act on the GLP-1 receptor only.
NICE / NHS context
- Tirzepatide for weight management: NICE TA1026, with a phased NHS rollout decided by NHS England commissioning policy.
- Semaglutide 2.4mg for weight management: NICE TA875, NHS access via Tier 3 specialist services after GP referral.
- Ozempic, Rybelsus and Nevolat: prescribed within their licensed indications under current NICE guidance and local commissioning rules.
Service-level costs
For UK private weight-management consultations, see the service-cost framework. The medicine itself is priced separately by the dispensing GPhC-registered pharmacy and is not displayed on TreatCompare’s consumer pages.
What to discuss with a UK prescriber
- Which medicine is licensed for your clinical question.
- Whether NHS-funded treatment is realistic before paying privately.
- The dose escalation schedule and tolerability monitoring approach.
- Common and serious side effects, and what to do if they occur.
For individual patient-information pages see Mounjaro, Wegovy, Ozempic, Rybelsus and Nevolat.
If you have spotted an error
Please tell us via the corrections route.
Frequently asked questions
What is a GLP-1 receptor agonist?
GLP-1 (glucagon-like peptide-1) receptor agonists are medicines that mimic the GLP-1 hormone, which is involved in regulating blood glucose, appetite and gastric emptying. They are licensed for type 2 diabetes and, in higher-dose formulations, for weight management.
Why does this article not show UK prices?
GLP-1 weight-management medicines are prescription-only medicines (POMs) in the UK. UK Human Medicines Regulations 2012 prohibit advertising POMs to the public, including price comparisons. TreatCompare does not display UK GLP-1 prices on consumer pages.
How are GLP-1 medicines accessed on the NHS?
NHS access is decided by NICE technology appraisals and NHS England commissioning policy. Tirzepatide (Mounjaro) is recommended under TA1026 with a cohort rollout. Semaglutide 2.4mg (Wegovy) is recommended under TA875 via Tier 3 specialist services. Speak to your GP for local availability.
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Weight Loss Injection Prices
Compare Mounjaro, Wegovy, Ozempic, and Nevolat prices from verified GPhC-registered UK pharmacies. Checked weekly.
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